MEDICINAL PLANTS AND THEIR IMPORTANCE
Medicinal
plants are important because they confer Medicinal activities due to presence
of Phytochemicals. Plant phytochemicals has been broadly classified into
Primary
constituents which
include the common sugars, amino acids, chlorophylls, proteins, purines and
pyrimidines of nucleic acids etc.
Secondary
constituents are
the remaining plant chemicals such as alkaloids, terpenes, flavonoids, lignans,
plant steroids, curcumines, saponins, phenolics, flavonoids and glucosides. The
activity of the phytochemicals depends on their structures.
Central
Drug Research Institute of India (CDRI):
This is located in Lucknow. Here
extensive research is done on the drugs their sources, extraction and effects.
Regular attempts are made to find out new medicines from herbs for treating
various diseases.
What are Secondary Metabolites?
Compounds that do not have direct physiological role in plants are secondary in function and are characterized as Secondary Metabolites.
Plants synthesize secondary
metabolites (small organic molecules) that are not required for their normal
growth or development but are essentially required for reproduction and defense
mechanism against bacteria, fungus, virus, vertebrates, etc. These products
have a great potential to act as drugs.
What does Secondary Metabolites do?
Disruption
of cell membrane functions and structure of microbes.
Interference
with intermediary metabolism
Interruption
of DNA/RNA synthesis and function
v
Interruption
of normal cell communication (quorum sensing)
v
Induction
of coagulation of cytoplasmic constituents
v Medicinal plants have shown
promising antimicrobial activities, anti-helminthic, anticancer, antidiarrheal
and antiviral activities.
Some
important secondary metabolites
Plant derived drug
|
Plant
|
Papaver somniferum
|
Codeine, Papaverine
|
Catharanthus roseus
|
Vinblastine and vincristine
|
Atropa belladonna
|
Tiotropium bromide
|
Why medicinal plants?
Used in drug development and drug
synthesis.
Some birds selected nested material
rich in antimicrobial activity for protection of their young ones.
Phytomedicine preparation:
According to the World Health Organization (WHO, 2001), phytomedicine is
defined as herbal preparations produced by subjecting plant materials to
extraction, fractionation, purification, concentration or other physical or
biological processes.
Classification: They are classified according to
the part used, habit, habitat, therapeutic value etc,
Classification
|
Example
|
Based on the part used
|
Leaf(Indigofera tinctoria,
Aloe vera), Flower (Biophytum sensityvum), Fruit (Solanum species) and
Seed (Datura stramonium). Root (Raulfia serpentina)
|
Based on the Habit
|
Herbs (Vernonia cineria), Shrubs
(Solanum species), Climbers
(Asparagus racemosus) and Trees (Azadirachta indica)
|
Based on the Ayurvedic
formulation
|
The three fruits of the
Triphala (Thriphalam)
Phyllanthus emblica (Nellikka/Amla),
Terminalia bellerica (Thannikka/Bahera) and Terminalia chebula
(Kadukka/Harar)
|
Comments
Post a Comment