Inhibitors of Electron Transport Chain in Mitochondria Important for Csir net, GATE, Dbt Jrf, Icmr, Tifr, iit jam exams

 

Site of Action	Inhibitor
COMPLEX-1	Rotenone, Amytal A, Piericidin
Complex II	Malonate
Complex II	Antimycin A, Myxothiazol
Complex IV	Cyanide, Azide, Carbon monoxide
Alternative oxidase	Salicylhydroxamic acid
F, of Fo-F,;-ATP synthase	Oligomycin

Fo of Fo-F;-ATP synthase	Dicyclohexyl carbodiimide
Adenylate transclocator	Bongkrekic acid, Carboxyatractyloside
Oxaloacetate translocator	Phthalonate
Malate translocator	Butyl malonate
Proton gradient	2,4-dinitrophenol, Carbonyl cyanide-m-chlorophenylhydrazone, Carbonyl cyanide p-trifluormethoxyphenylhydrazone, Ammonium chloride, Methyl amine